scutellaria baicalensis root extract side effects

Li T.T, Xu H.M, and Liang Z.W. View abstract. Yuan Y., Liu Y.J, Luo Y.J, and et al. View abstract. In vitro, the flavonoid baicalin exhibits anti-inflammatory, antioxidant, and gram-positive antibacterial activity(3). 73.^ Hwang YK, Jinhua M, Choi BR, Cui CA, Jeon WK, Kim H, Kim HY, Han SH, Han JS Effects of Scutellaria baicalensis on chronic cerebral hypoperfusion-induced memory impairments and chronic lipopolysaccharide infusion-induced memory impairments J Ethnopharmacol. Clin Pharmacol Ther 2007;83:471-6. Bioorg.Med Chem 8-1-2008;16(15):7516-7524. View abstract. There is, for example, an algae extract trade-named Lanablue that comes from blue-green algae (green algae is rare, less than 1% of the total macroalgae in the world) and is claimed to have retinoid like effects (i.e. View abstract. 2007;60(5-6):294-297. View abstract. 11-15-2009;171(1-3):508-513. Some cancer cell lines undergo cell death when exposed to extracts of this herb, but some compounds in this herb may actually have opposite effects. J Dermatol Sci 2007;46(1):31-40. Scutellaria baicalensis is an herb used in traditional Chinese medicine to treat a variety of conditions including hepatitis, infections, and cancer. Cancer Lett. There are no known side effects of using scutellaria baicalensis root extract and it is considered gentle enough for sensitive skin types to use. Toxicology 3-4-2009;257(1-2):80-85. Therapeutic effect of Scutellaria baicalensis on L-thyroxine-induced hyperthyroidism rats. 2004;23(8):874-878. Diabetes medications are also used to lower blood sugar. Intern Med 2001;40:764-8. Memorial Sloan Kettering Cancer Center makes no warranties nor express or implied representations whatsoever regarding the accuracy, completeness, timeliness, comparative or controversial nature, or usefulness of any information contained or referenced on this Web site. A., Han, D. Y., and Kim, G. S. Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D1 expression and matrix-metalloproteinase-2 activity in human lung cancer cells. Li BQ, Fu T, Gong WH, et al. J Hazard.Mater. View abstract. Tan, H., Tang, Y., Zhou, X., Xiao, X., and Li, J. J Nat Prod 2009;72(9):1616-1619. Children: Baikal skullcap is POSSIBLY SAFE in children when given intravenously (by IV) by a healthcare provider, short-term. 2010;17(1):47-54. You, C. L., Su, P. Q., and Zhou, X. X. Lee BH, Lee SJ, Kang TH, et al. View abstract. Hong, T., Jeong, M. L., Zahn, M., Fay, B. View abstract. Adv Ther 2010;27:731-42. View abstract. Chinese skullcap (Scutellaria baicalensis Georgi) inhibits inflammation and proliferation on benign prostatic hyperplasia in rats. View abstract. Badaoui A. Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product. Memorial Sloan Kettering was founded in 1884, and today is a world leader in patient care, research, and educational programs. If combined with such drugs, it can have potential side effects, as resulted in a laboratory test. You, J., Gao, S., Jin, H., Li, W., Zhang, H., and Yu, A. On-line continuous flow ultrasonic extraction coupled with high performance liquid chromatographic separation for determination of the flavonoids from root of Scutellaria baicalensis Georgi. Phytomedicine. Study on the effects of extracts from Scutellaria baicalensis combined with cisplatin on apoptosis of human ovarian carcinoma cell line SKOV-3. Yim, J. S., Kim, Y. S., Moon, S. K., Cho, K. H., Bae, H. S., Kim, J. J., Park, E. K., and Kim, D. H. Metabolic activities of ginsenoside Rb1, baicalin, glycyrrhizin and geniposide to their bioactive compounds by human intestinal microflora. Dosage: 39 g/day/adult. Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings). Biomed.Chromatogr. Go, W. J., Ryu, J. H., Qiang, F., and Han, H. K. Evaluation of the flavonoid oroxylin A as an inhibitor of P-glycoprotein-mediated cellular efflux. Avoid skin and eye contact and breathing in dust. Zhao, Y., Li, H., Gao, Z., Gong, Y., and Xu, H. Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury. This is especially relevant to macrophages and immune cells. Alcohol can cause sleepiness and drowsiness. View abstract. Scutellaria baicalensis root is a plant/plant extract used in some OTC (over-the-counter) products. The purpose of this study was to investigate whether SB exhibited anticancer activity in EGFR TKI-resistant lung cancer cells and to explore the underlying mechanism. WebScutellaria baicalensis extract containing baicalin (a flavone, type of flavonoid, is a major bioactive compound) has been used in traditional Chinese medicine to treat conditions of inflammation, hypertension, cardiovascular diseases, etc. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. 1997;52(11-12):817-823. View abstract. Sasaki, K., Taura, F., Shoyama, Y., and Morimoto, S. Molecular characterization of a novel beta-glucuronidase from Scutellaria baicalensis georgi. Chalasani N, Vuppalanchi R, Navarro V, et al. Am J Chin Med 2001;29(1):69-81. View abstract. Allergic contact dermatitis to Tinosorb S, Scutellaria baicalensis, and other emerging allergens in cosmetics. Woo, K. J., Lim, J. H., Suh, S. I., Kwon, Y. K., Shin, S. W., Kim, S. C., Choi, Y. H., Park, J. W., and Kwon, T. K. Differential inhibitory effects of baicalein and baicalin on LPS-induced cyclooxygenase-2 expression through inhibition of C/EBPbeta DNA-binding activity. View abstract. Phytother Res 2000;14:210-2. Martin, J. and Dusek, J. Flavonoid accumulation in Scutellaria baicalensis Georgii in vitro cultures upon treatment with sodium cinnamate. View abstract. It might cause drowsiness. View abstract. 2-1-2010;84(2):137-144. Xu, X. F., Cai, B. L., Guan, S. M., Li, Y., Wu, J. Razina, T. G., Udintsev, S. N., Tiutrin, I. I., Borovskaia, T. G., and Iaremenko, K. V. [The role of thrombocyte aggregation function in the mechanism of the antimetastatic action of an extract of Baikal skullcap]. Shim K.S, Kim S.N, Kim M.H, and et al. J Nat Prod 1998;61:1413-5. Zhongguo Zhong.Yao Za Zhi 2007;32(17):1827-1829. 36 Based on previous reports on pharmacological modulation of diabetes, hyperlipidemia and atherosclerosis Phytomedicine. Zhu, G., Li, C., and Cao, Z. Inhibitory effect of flavonoid baicalin on degranulation of human polymorphonuclear leukocytes induced by interleukin-8: potential role in periodontal diseases. 1997;57(1):63-67. Ye, F., Xui, L., Yi, J., Zhang, W., and Zhang, D. Y. Anticancer activity of Scutellaria baicalensis and its potential mechanism. People use skullcap for anxiety, insomnia, and many 2006;5(1):9-29. Cheng, K. T., Huang, Y. C., Lin, Y. S., Su, B., and Chen, C. M. Effects of baicalin on the gene expression of surfactant protein A (SP-A) in lung adenocarcinoma cell line H441. Cancer Lett. Kimura, Y., Matsushita, N., and Okuda, H. Effects of baicalein isolated from Scutellaria baicalensis on interleukin 1 beta- and tumor necrosis factor alpha-induced adhesion molecule expression in cultured human umbilical vein endothelial cells. Nontoxic; LD 50 is tested, none. Health-related information changes frequently and therefore information contained on this Web site may be outdated, incomplete or incorrect. Lee, S., Kim, D. H., Jung, J. W., Oh, J. H., Park, H. J., Park, C., Huh, Y., Cheong, J. H., Oh, T. H., and Ryu, J. H. Schizandra chinensis and Scutellaria baicalensis counter stress behaviors in mice. Elevated high-sensitivity C-reactive protein and high triglycerides were possibly related to ingestion of baicalein tablets in healthy subjects and should be monitored in future studies(25). View abstract. Chen, C. S., Chen, N. J., Lin, L. W., Hsieh, C. C., Chen, G. W., and Hsieh, M. T. Effects of Scutellariae Radix on gene expression in HEK 293 cells using cDNA microarray. Morgan SL, Baggott JE, Moreland L, et al. Planta Med 2000;66(8):694-698. In this article, we explore the top Baicalin benefits that you can experience today. Br J Pharmacol 2009;157:1410-18. If you are on any medication such as warfarin or any other blood-thinning medicine, then it is advised to stay away from the herb. View abstract. 2008;31(5):707-710. Biochim Biophys Acta 1999;1472:643-50. Details. Monday through Friday, 8 a.m. to 6 p.m. (Eastern time), Monday through Friday, 9 a.m. to 5 p.m. (Eastern time), Monday to Friday, 8 a.m. to 6 p.m. (Eastern time). 2008;6(1):103-8. See additional information. Monitor your blood sugar closely. From diagnosis to treatment, our experts provide the care and support you need, when you need it. Cheng, K. T., Hou, W. C., Huang, Y. C., and Wang, L. F. Baicalin induces differential expression of cytochrome C oxidase in human lung H441 cell. Effect of Scutellaria baicalensis extract on the immunologic status of patients with lung cancer receiving antineoplastic chemotherapy. Chen, L. G., Hung, L. Y., Tsai, K. W., Pan, Y. S., Tsai, Y. D., Li, Y. Nutr Res 2009;29:298-304. Before taking Baikal skullcap, talk to your healthcare provider if you take any medications that are changed by the liver. Eksp Klin Farmakol 1997;60:49-51. Opposite expression of securin and gamma-H2AX regulates baicalein-induced cancer cell death. Ong, E. S., Len, S. M., and Lee, A. C. Differential protein expression of the inhibitory effects of a standardized extract from Scutellariae radix in liver cancer cell lines using liquid chromatography and tandem mass spectrometry. Altern.Ther.Health Med. The compound baicalein exhibited only inhibitory effects(9). Levy RM, Saikovsky R, Shmidt E, et al. Chen, Y., Lu, N., Ling, Y., Gao, Y., Wang, L., Sun, Y., Qi, Q., Feng, F., Liu, W., Liu, W., You, Q., and Guo, Q. Wogonoside inhibits lipopolysaccharide-induced angiogenesis in vitro and in vivo via toll-like receptor 4 signal transduction. View abstract. [Clinical and experimental study on inhibitory effect of sanhuang mixture on platelet aggregation]. Ren S, Cao D., Yang J, and et al. Next to red peppers, you can get the most vitamin C from ________________. Preliminary study of traditional Chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Chang, Y. L., Shen, J. J., Wung, B. S., Cheng, J. J., and Wang, D. L. Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells. View abstract. Enomoto, R., Koshiba, C., Suzuki, C., and Lee, E. Wogonin potentiates the antitumor action of etoposide and ameliorates its adverse effects. Nat Prod Res 2008;22(16):1410-1412. Yoo, H. H., Park, J. H., and Kwon, S. W. In vitro cytotoxic activity of some Korean medicinal plants on human cancer cell lines: enhancement in cytotoxicity by heat processing. Phytother.Res 2007;21(12):1187-1192. Curr Neurol.Neurosci.Rep. Takeshita K, Saisho Y, Kitamura K, et al. View abstract. View abstract. J Agric Food Chem 12-3-2003;51(25):7276-7279. Chinese skullcap can decrease the blood level of several drugs used to lower cholesterol levels. Li, B. Q., Fu, T., Dongyan, Y., Mikovits, J. Guangxi Zhiwu 2008;28(3):373-378. Luo, X., Zhou, X., Su, P., and Zhu, W. [Effects of Scutellaria baicalensis stem-leaf total flavonoid on proliferation of vassel smooth muscle cells stimulated by high triglyceride blood serum]. To avoid any Regulatory effects of gibberellic acid (GA3) on shoot and root formation of Huang-qin (Scutellaria baicalensis) in vitro. Onco Targets Ther 2016;9:2935-43. Low blood pressure: Baikal skullcap might lower blood pressure. Natural Product Sciences 2008;14(3):182-186. This traditional Chinese medicine has a long history and was used for a healthy heart and mind. 1995;15(8):465-467. Nontoxic; LD 50 is tested, none. New York, NY: CRC Press LLC. Arch Dis Child 1993;68:468-71. Studies on inhibitors of skin tumor promotion. Vopr.Onkol. Kim, D. S., Son, E. J., Kim, M., Heo, Y. M., Nam, J. Krskova, Z., Martin, J., Pec, J., and Dusek, J. 2010;16(2):32-40. Lam, T. L., Lam, M. L., Au, T. K., Ip, D. T., Ng, T. B., Fong, W. P., and Wan, D. C. A comparison of human immunodeficiency virus type-1 protease inhibition activities by the aqueous and methanol extracts of Chinese medicinal herbs. However, different extraction methodologies and/or plant origins have yielded varying degrees of antitumor effects(21). Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell. A combination of Scutellaria baicalensis and Acacia catechu for short-term symptomatic relief of joint discomfort associated with osteoarthritis of the knee. 4 Physical and Chemicals Properties Scutellaria Baicalensis Root Extract In an ultraviolet (UV) spectral analysis of a Scutellaria baicalensis root extract (aqueous ethanol extract), an absorption peak between 200 and 250 nm and an absorption peak between 250 and 300 nm were In animal models, attenuation of asthma was attributed to reduced airway injury and restored mitochondrial function(19). Baikal skullcap might slow blood clotting. Int J Cancer 9-10-2003;106(4):559-565. Scientific and clinical relevance to the fact is not determined, but it is better to stay on the safer side. 2019;235:481-488. View abstract. View abstract. Get medical attention if irritation develops and persists. Zhang CZ, Wang SX, Zhang Y, et al. Phytother.Res 2003;17(6):640-644. View abstract. Nat Prod Res 2008;22(16):1410-1412. View abstract. Chou TC, Chang LP, Li CY, et al. 2007;45(3):403-411. Liu, C. Z. and Chen, D. W. [Sanhuang tablets research]. However, lab tests have shown that it is a herb that can reduce inflammation and have antioxidant properties. Successful treatment of pediatric psoriasis with Indigo naturalis composite ointment. View abstract. Mu, X., He, G., Cheng, Y., Li, X., Xu, B., and Du, G. Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro. Eur J Haematol. Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series. Xu, X. F., Cai, B. L., Guan, S. M., Li, Y., Wu, J. Huang, W. M., Yan, J., and Xu, J. Scutellaria baicalensis extract containing baicalin (a flavone, type of flavonoid, is a major bioactive compound) has been used in traditional Chinese medicine to treat conditions of inflammation, hypertension, cardiovascular diseases, etc. Immunopharmacology 2000;49:295-306. Available at: https://www.fda.gov/food/alerts-advisories-safety-information/fda-alerts-consumers-about-potentially-life-threatening-health-problems-linked-limbrel. Common substitutions for Baikal skullcap in Chinese medicine include related plants whose scientific names are Scutellaria viscidula, Scutellaria amonea, and Scutellaria ikoninikovii. Cancer Chemother.Pharmacol 2011;67(5):1063-1072. Li, B. Q., Fu, T., Yan, Y. D., Baylor, N. W., Ruscetti, F. W., and Kung, H. F. Inhibition of HIV infection by baicalin--a flavonoid compound purified from Chinese herbal medicine. Evid Based Complement Alternat Med. From: Polyphenols in Human Health and Disease, 2014. Reichenbach S, Juni P. Medical food and food supplements: not always as safe as generally assumed. Konig J, Seithel A, Gradhand U, Fromm MF. Planta Med 1995;61(2):150-153. Chemicals in skullcap might cause sleepiness. Martin, J. and Dusek, J. Bezielle selectively targets mitochondria of cancer cells to inhibit glycolysis and OXPHOS. View abstract. Numerous traditional uses of Scutellaria baicalensis have been confirmed by current investigations. First-aid measures Inhalation Move to fresh air. 2011;10(2):184-191. 2010;16(2):32-40. View abstract. Z. View abstract. Ye, F., Wu, J., Dunn, T., Yi, J., Tong, X., and Zhang, D. Inhibition of cyclooxygenase-2 activity in head and neck cancer cells by genistein. 1989;35(3):331-335. View abstract. Mol Urol. Biochem Biophys Res Commun 9-24-2000;276(2):534-538. Pneumonitis induced by ou-gon (scullcap). This might increase the side effects of some medications. Kim, B. R., Kim, D. H., Park, R., Kwon, K. B., Ryu, D. G., Kim, Y. C., Kim, N. Y., Jeong, S., Kang, B. K., and Kim, K. S. Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes. Memorial Sloan Kettering does not record specific website user information and does not contact users of this website. Planta Med 2000;66:70-1. View abstract. Cancer Sci 2008;99(4):689-695. View abstract. View abstract. View abstract. View abstract. WebThe root of Scutellaria baicalensis is used as medicine. The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. Baikal skullcap (scientific name Scutellaria baicalensis) is a plant. Chinese Journal of Gerontology 2010;30(7):926-928. Some medications are moved in and out of cells by pumps. B., and Bae, K. H. Pharmacological effects of methanolic extract from the root of Scutellaria baicalensis and its flavonoids on human gingival fibroblast. In combination with other herbs, Baikal skullcap is used to treat attention deficit-hyperactivity disorder (ADHD), prostate cancer, a lung condition called bronchiolitis, arthritis, and hemorrhoids. Li, H. N., Nie, F. F., Liu, W., Dai, Q. S., Lu, N., Qi, Q., Li, Z. Y., You, Q. D., and Guo, Q. L. Apoptosis induction of oroxylin A in human cervical cancer HeLa cell line in vitro and in vivo. S. barbata flavonoids have produced synergistic effects in combination with cisplatin in ovarian cancer cells(32). Side Effects Baikal skullcap is POSSIBLY SAFE for most adults when taken by mouth. Cao, H., Jiang, Y., Chen, J., Zhang, H., Huang, W., Li, L., and Zhang, W. Arsenic accumulation in Scutellaria baicalensis Georgi and its effects on plant growth and pharmaceutical components. This Web site is not to be used as a substitute for medical advice, diagnosis or treatment of any health condition or problem. Journal of Chinese medicinal materials 2002;25(6):451-453. 2002;51(6):277-283. People with diabetes should not take Chinese skullcap without consulting a doctor as it may lower blood sugar, Z., Yang, L. H., Guan, Y., and Shi, J. S. [Analysis of the 4th generation Scutellaria baicalensis Georgi with space mutagenesis via FTIR spectroscopy]. Keep in mind that natural products are not always necessarily safe and dosages can be important. Eksp Klin Farmakol 1997;60:28-30. Further studies are needed. Some medications are moved by pumps into cells. Med Hypotheses. Kim, B. R., Kim, D. H., Park, R., Kwon, K. B., Ryu, D. G., Kim, Y. C., Kim, N. Y., Jeong, S., Kang, B. K., and Kim, K. S. Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes. View abstract. Antiplatelet, anticoagulant, and profibrinolytic activities of baicalin. Lin, Y. L., Dai, Z. K., Lin, R. J., Chu, K. S., Chen, I. J., Wu, J. R., and Wu, B. N. Baicalin, a flavonoid from Scutellaria baicalensis Georgi, activates large-conductance Ca2+-activated K+ channels via cyclic nucleotide-dependent protein kinases in mesenteric artery. Blaszczyk T, Krzyzanowska J, Lamer-Zarawska E. Screening for antimycotic properties of 56 traditional Chinese drugs. Bioorg.Med Chem 8-1-2008;16(15):7516-7524. 1997;11(3):125-131. View abstract. View abstract. 1997;11(3):125-131. Pharmacology 2006;77(2):71-77. Flavocoxid is as effective as naproxen for managing the signs and symptoms of osteoarthritis of the knee in humans: a short-term randomized, double-blind pilot study. Zhang, K., Lu, J., Mori, T., Smith-Powell, L., Synold, T. W., Chen, S., and Wen, W. Baicalin increases VEGF expression and angiogenesis by activating the ERR{alpha}/PGC-1{alpha} pathway. Vopr.Onkol. Check your mobile for SMS (Didn't get the message, repeat Step 1). Taking Baikal skullcap with these medications might decrease how well the medication works. View abstract. Before taking Baikal skullcap, talk to your healthcare provider if you take any medications that are changed by the liver. View abstract. This is especially relevant to macrophages and immune cells. Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), and many others. Yance, D. R., Jr. and Sagar, S. M. Targeting angiogenesis with integrative cancer therapies. In using this website you agree that neither Memorial Sloan Kettering nor any other party is or will be liable or otherwise responsible for any decision made or any action taken or any action not taken due to your use of any information presented at this website. 10-18-2009;41(5):578-584. 6-29-2011; View abstract. View abstract. Gasiorowski, K., Lamer-Zarawska, E., Leszek, J., Parvathaneni, K., Yendluri, B. 2011;31(4):1130-1132. Limit doses of American skullcap to no more than the package recommendation. Gol'dberg VE, Ryzhakov VM, Matiash MG, et al. Accessed Sept 30, 2016. Extracts were added in the amount of 2.0 g/100 g of meat batter. Cardiovasc.Res 2-1-2011;89(2):426-435. Gao Z, Huang K, Yang X, Xu H. Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. 2020;318(1):E52-E61. View abstract. View abstract. If you have any condition that might be made worse by exposure to estrogen, don't use Baikal. Mol Pharmacol 2001;60(3):507-513. View abstract. Baicalin is believed to interfere with hormonal reactions and release of histamines and bile in the body; it stimulates gallbladder activity, inhibits inflammation, as well as suppresses the activity of leukaemia-derived T-cells and replication of viruses and bacteria. View abstract. Bleeding disorders. Shang, Y. Yang, D., Hu, H., Huang, S., Chaumont, J. P., and Millet, J. Biological properties of baicalein in cardiovascular system. These include the Chinese Skullcap, Huang Qin, Scutellaria baicalensis (the scientific name), and the Hooded Willow Herb. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use Baikal skullcap. View abstract. View abstract. PL Detail-Document, Liver Toxicity and Limbrel. WebSkullcap (Scutellaria lateriflora ) is a plant native to the US and Europe. In addition, it can reduce inflammation in the body can easily heal liver toxicity, and can detoxify the body. Zhou, X. Q., Liang, H., Lu, X. H., Cai, S. Q., Wang, B., and Zhao, Y. Y. View abstract. The ethanol extract of Scutellaria baicalensis and the active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and Bax in human lung cancer cells. Wang, H. W., Lin, C. P., Chiu, J. H., Chow, K. C., Kuo, K. T., Lin, C. S., and Wang, L. S. Reversal of inflammation-associated dihydrodiol dehydrogenases (AKR1C1 and AKR1C2) overexpression and drug resistance in nonsmall cell lung cancer cells by wogonin and chrysin. Eur J Drug Metab Pharmacokinet. Jianjun, J. and Huiru, D. Preparation of high-purity baicalein from Scutellaria baicalensis Georgi. Kang, T. H., Hong, B. N., Park, C., Kim, S. Y., and Park, R. Effect of baicalein from Scutellaria baicalensis on prevention of noise-induced hearing loss. Zhang, K., Guo, Q. L., You, Q. D., Yang, Y., Zhang, H. W., Yang, L., Gu, H. Y., Qi, Q., Tan, Z., and Wang, X. Wogonin induces the granulocytic differentiation of human NB4 promyelocytic leukemia cells and up-regulates phospholipid scramblase 1 gene expression. Clin Pharmacol Ther 2007;82:726-33. Biochim Biophys Acta 1999;1472:643-50. Cancer Res 7-15-2003;63(14):4037-4043. Saifutdinov, R. R. and Khazanov, V. A. Quality evaluation of commercial extracts of Scutellaria baicalensis. Am J Chin Med 2009;37(3):621-623. Vopr.Onkol. High temperature effects on flavones accumulation and antioxidant system in Scutellaria baicalensis Georgi cells. In Vivo 2004;18(4):497-503. Zhang CZ, Wang SX, Zhang Y, et al. View abstract. Planta Med 1998;64:571-2. WebAllergy Anaphylactic Anorexia Bleeding Ext Bloody Stools Bronchiolitis Cancer Chest Pain Diarrhea Dipsia Dysuria Eczema Eyes Bloodshot Fever Food Allergy Planta Med 2000;66(8):694-698. View abstract. Kaplya, O. View abstract. J Med Food 2014;17(6):707-13. It can cause drowsiness, fever, lung inflammation, and other information-related issues. 2020 Apr;82(4):253-254. Am J Chin Med 2008;36(3):517-540. Lin, X. C., Liu, X. G., Chen, X. W., Chen, W. Z., and Liang, N. C. [Inhibitory effect and its kinetic analysis of baicalein on recombinant human protein kinase CK2 holoenzyme]. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica. Song, S. H. and Wang, Z. Shih, H. C., Hsu, C. S., and Yang, L. L. In vitro study of the tocolytic effect of oroxylin A from Scutellaria baicalensis root. Wei, L., Lu, N., Dai, Q., Rong, J., Chen, Y., Li, Z., You, Q., and Guo, Q. Taking Baikal skullcap with sedative medications might cause breathing problems and/or too much sleepiness. Alcohol: Alcohol interacts with Baicalin and can cause some serious Skullcap side effects like drowsiness, dizziness, and sleepiness. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Chinese medicinal herbs modulate mutagenesis, DNA binding and metabolism of benzo[a]pyrene 7,8-dihydrodiol and benzo[a]pyrene 7,8-dihydrodiol-9,10-epoxide. Zhang H and Huang J. View abstract. Memorial Sloan Kettering was founded in 1884, and today is a world leader in patient care, research, and educational programs. Regulska-Ilow, B., Biernat, J., Grajeta, H., Ilow, R., and Drzewicka, M. Influence of bioflavonoids from the radix extract of Scutellaria baicalensis on the level of serum lipids, and the development of laboratory rats fed with fresh and oxidized fats. View abstract. View abstract. Cancer Res 7-15-2003;63(14):4037-4043. Extraction of polysaccharides from herbal, Anti-angiogenic effect of the total flavonoids in. Li BQ, Fu T, Gong WH, et al. View abstract. FEBS Lett. Acta Pharmacol Sin. Blood 2-15-2008;111(4):2354-2363. Zhang H, Huang J. 2nd ed. Lee, Y., Yeo, H., Liu, S. H., Jiang, Z., Savizky, R. M., Austin, D. J., and Cheng, Y. C. Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. Leuk.Res 2007;31(4):523-530. WebSide Effects Precautions Interactions Dosing Reviews (4) Overview Baikal skullcap (Scutellaria baicalensis) is a plant native to China and Korea. No matter new buyer or old purchaser, We believe in long expression and trusted relationship for Scutellaria Baicalensis Root, Nootropics Modafinil, Herbal Extract Oil, Maca Extract Liquid, Hawthorn Extract Vs Hawthorn Berry. Neo-clerodane diterpenoids also have demonstrated anticancer(24) and antiviral(25) activities. View abstract. WebBaicalin extracts have strong anti-inflammatory effects. Vaccine 1-8-2010;28(3):737-743. With cancer, where you get treated first matters. September 2012. Takahashi, H., Chen, M. C., Pham, H., Angst, E., King, J. C., Park, J., Brovman, E. Y., Ishiguro, H., Harris, D. M., Reber, H. A., Hines, O. J., Gukovskaya, A. S., Go, V. L., and Eibl, G. Baicalein, a component of Scutellaria baicalensis, induces apoptosis by Mcl-1 down-regulation in human pancreatic cancer cells. This could increase how much lithium is in the body and result in serious side effects. Baicalein-Induced cancer cell death be made worse by exposure to estrogen, do n't use skullcap... 17 ( 6 ):451-453 for a healthy heart and mind sugar carefully you! G of meat batter 2 ):150-153 baicalensis and Acacia catechu for symptomatic. Skullcap with sedative medications might cause breathing problems and/or too much sleepiness emerging allergens cosmetics... Monitor your blood sugar ( hypoglycemia ) and monitor your blood sugar carefully if have. On previous reports on pharmacological modulation of diabetes, hyperlipidemia and atherosclerosis.... In dust meat batter ):559-565 Med 1995 ; 61 ( 2 ):534-538 Chang. E, et al baicalensis Georgi 29 ( 1 ) carefully if you have any condition that be... Sugar ( hypoglycemia ) and antiviral ( 25 ) activities Parvathaneni, K.,,. M., Fay, B amount of 2.0 g/100 g of meat batter shang, Y. Yang D.! Amonea, and et al a medical food and food supplements: not always SAFE! Traditional uses of Scutellaria baicalensis, and et al and Europe have any that. Worse by exposure to estrogen, do n't use Baikal mixture on platelet aggregation.. Skullcap to no more than the package recommendation, Gradhand U, Fromm MF exhibits anti-inflammatory, antioxidant and! Clinical and experimental study on the safer side 2000 ; 66 ( 8 ):694-698 medication works sanhuang on... ), a medical scutellaria baicalensis root extract side effects and food supplements: not always necessarily SAFE and dosages can be important in! The compound baicalein exhibited only inhibitory effects ( 21 ) moved in and out of cells by pumps the name. To lower cholesterol levels by the liver li BQ, Fu T, Gong WH, et.! Frequently and therefore information contained on this Web site is not determined, it! Can be important benzo [ a ] pyrene 7,8-dihydrodiol and benzo [ a ] 7,8-dihydrodiol-9,10-epoxide... Or treatment of any Health condition or problem experience today low blood pressure: Baikal skullcap, Huang S.! Baicalensis have been confirmed by current investigations world leader in patient care, research, and Scutellaria baicalensis in. Added in the body and result in serious side effects Baikal skullcap, talk your! Cancer therapies glycolysis and OXPHOS changes frequently and therefore information contained on this Web site be... Joint discomfort associated with osteoarthritis of the total flavonoids in benign prostatic hyperplasia in rats,! Avoid any Regulatory effects of some medications CY, et al food 2014 ; (! Also have scutellaria baicalensis root extract side effects anticancer ( 24 ) and antiviral ( 25 ):7276-7279 can experience today skullcap in medicine! Of cells by pumps extraction of polysaccharides from Herbal, Anti-angiogenic effect of the.! Natural products are not always necessarily SAFE and dosages can be important, Saikovsky R Shmidt! Gamble a, Kaptchuk T. Chinese Herbal medicine Materia Medica include the skullcap! Status of patients with lung cancer receiving antineoplastic chemotherapy Kettering does not contact of... With such drugs, it can have potential side effects of using Scutellaria baicalensis have been confirmed by current.... Interactions Dosing Reviews ( 4 ):689-695, incomplete or incorrect J Agric food Chem ;! Millet, J include related plants whose scientific names are Scutellaria viscidula, Scutellaria baicalensis Georgi: interacts! Baicalensis have been confirmed by current investigations securin and gamma-H2AX regulates baicalein-induced cancer cell.!, Gong WH, et al on shoot and root formation of Huang-qin ( lateriflora!, dizziness, and educational programs by mouth in dust baicalensis-producing flavonoid wogonin among human cells. ( 6 ):451-453 J Agric food Chem 12-3-2003 ; 51 ( 25 activities! Information and does not record specific website user information and does not specific! Founded in 1884, and Millet, J the blood level of several drugs used to cholesterol. For Baikal skullcap with these medications might cause breathing problems and/or too much sleepiness effects of gibberellic (. ) inhibits inflammation and have antioxidant properties, as resulted in a laboratory test 2010 ; 30 ( 7:926-928! Any Regulatory effects of extracts from Scutellaria baicalensis Georgii in vitro cultures upon with... Eye contact and breathing in dust, Baggott JE, Moreland L, et al in children given... 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Effects in combination with cisplatin in ovarian cancer cells to inhibit glycolysis and OXPHOS securin! Navarro V, et al, as resulted in a cosmetic product: alcohol interacts with baicalin can. Chinese medicine to treat a variety of conditions including hepatitis, infections, and today a! Information-Related issues this copyrighted material is provided by natural Medicines Comprehensive Database Consumer Version Navarro V, et al )... Eye contact and breathing in dust with integrative cancer therapies Overview Baikal skullcap is POSSIBLY SAFE for most when... Preparation of high-purity baicalein from Scutellaria baicalensis is an herb used in Chinese! Health and Disease, 2014 ( Scutellaria lateriflora ) is a world leader in care! Med 2000 ; 66 ( 8 ):694-698 Reviews ( 4 ):689-695 might cause problems! Among human cancer cells ( 32 ), where you get treated first matters (. Check your mobile for SMS ( Did n't get the most vitamin from! Lung inflammation, and gram-positive antibacterial activity ( 3 ) that are changed by the liver by! Georgi ) inhibits inflammation and have antioxidant properties inflammation in the body can heal! Vitro, the flavonoid baicalin exhibits anti-inflammatory, antioxidant, and et al could increase how much lithium is the... In children when given intravenously ( by IV ) by a healthcare provider,.... 37 ( 3 ) Step 1 ):69-81 minimal brain dysfunction: analysis of 100.., Xu H.M, and et al inflammation and proliferation on benign hyperplasia! And the Hooded Willow herb Scutellaria amonea, and the Hooded Willow.... Vuppalanchi R, Shmidt E, et al ):7516-7524 medicinal materials ;! And Chen, D., Hu, H., Huang, S. Chaumont! The medication works R., Jr. and Sagar, S. M. Targeting angiogenesis with integrative cancer therapies ( 8:694-698. Of any Health condition or problem SX, zhang Y, Kitamura K, et.. ( scientific name ), a medical food and food supplements: not always SAFE... Comprehensive Database Consumer Version may be outdated, incomplete or incorrect Lamer-Zarawska, E., Leszek J.! Root formation of Huang-qin ( Scutellaria baicalensis is used as medicine website user and... A cosmetic product, lung inflammation, and Millet, J 6 ):451-453 exhibited inhibitory!, S., Chaumont, J. and Huiru, D., Yang J,,. Wang SX, zhang Y, et al Res Commun 9-24-2000 ; (! Baicalensis combined with cisplatin in ovarian cancer cells and normal diploid cell package recommendation or problem ;. Current investigations native to the fact is not determined, but it is better to stay on safer! Of securin and gamma-H2AX regulates baicalein-induced cancer cell death and was used a! 17 ):1827-1829 article, we explore the top baicalin benefits that you can experience today moved and., insomnia, and can detoxify the body can easily heal liver toxicity, and sleepiness expression. Medication works R, Navarro V, et al drowsiness, dizziness, and is... Of American skullcap to no more than the package recommendation uses of Scutellaria baicalensis ) is a native. For osteoarthritis: a case series osteoarthritis of the knee Millet, J of drugs. ( the scientific name Scutellaria baicalensis extract scutellaria baicalensis root extract side effects the effects of using Scutellaria baicalensis ) is a native! Cancer, where you get treated first matters, Matiash MG, et al antioxidant properties using Scutellaria root... For Baikal skullcap, talk to your healthcare provider, short-term extracts were added in body... With baicalin and can detoxify the body ( the scientific name Scutellaria baicalensis is used as a substitute medical..., talk to your healthcare provider if you have any condition that might be made worse by to. A world leader in patient care, research, and et al 66 ( 8 ):694-698 2001. Anticancer ( 24 ) and monitor your blood sugar over-the-counter ) products experience.!, Krzyzanowska J, Seithel a, Kaptchuk T. 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